Essential Biochemistry - Connective Tissue (Section 2 - No. 13)
What is the primary genetic defect in osteogenesis imperfecta?
Mutation in fibrillin
Defect in elastin production
Multiple genetic defects in type-I collagen synthesis
Deficiency in vitamin C
説明
Osteogenesis imperfecta is caused by genetic defects in type-I collagen synthesis.